Some medications can harm the kidneys, especially if taken in high doses, for a long time, or by people who already have kidney disease. However, you shouldn’t stop any prescribed medication without speaking to your healthcare provider.
Here are eight commonly discussed medications or medication classes that can affect kidney health:
- Ibuprofen – A common pain reliever that can reduce blood flow to the kidneys, especially with dehydration or long-term use.
- Naproxen – Another NSAID with similar kidney risks.
- Diclofenac – An NSAID that may increase the risk of kidney injury, particularly with prolonged use.
- Celecoxib – A prescription NSAID that can also affect kidney function in susceptible people.
- Certain antibiotics, such as Gentamicin – Can be toxic to the kidneys and require careful monitoring.
- Vancomycin – Another antibiotic that may affect the kidneys, especially at high doses or in combination with other kidney-toxic drugs.
- Lithium – Used for some mental health conditions and can cause kidney damage with long-term use if not monitored.
- Cisplatin – A chemotherapy medication known to have potential kidney toxicity, with preventive measures typically used during treatment.
How to reduce your risk
- Take medications only as directed.
- Stay well hydrated unless your doctor has advised you to limit fluids.
- Avoid taking multiple NSAIDs at the same time.
- Tell your healthcare provider about all medicines and supplements you use.
- If you have kidney disease, diabetes, or high blood pressure, ask whether any medication needs dose adjustments.
Many viral posts claim that certain pills “destroy your kidneys.” The reality is more nuanced: these medications can be very safe and effective when used appropriately, but some carry a higher risk of kidney injury under certain circumstances or without proper monitoring. If you’re concerned about a specific medication, I can explain its kidney risks in more detail.
