That headline is oversimplified and potentially misleading.
The truth is that some medications can affect the kidneys, especially in high doses, with long-term use, or in people who already have kidney disease. But it does not mean everyone should avoid them.
Some commonly discussed examples include:
- NSAID pain relievers such as Ibuprofen and Naproxen
- Certain antibiotics
- Some antiviral medications
- Some diuretics (“water pills”)
- Certain blood pressure medications (which can affect kidney function tests, though they often protect kidneys long-term)
- Some chemotherapy drugs
- Lithium
- Some contrast dyes used in medical imaging
Important context
- Many of these medications are safe and beneficial when used appropriately.
- The risk depends on factors such as age, hydration, dosage, other medications, and existing kidney disease.
- People with healthy kidneys can often take these medicines without problems when following medical advice.
Warning signs to discuss with a doctor
Seek medical advice if you develop:
- Reduced urination
- Swelling of the legs or feet
- Unusual fatigue
- Persistent nausea
- Sudden changes in kidney blood test results
Bottom line
A headline like “Eight pills you shouldn’t take” is usually trying to attract clicks. A more accurate statement would be:
“Some medications can increase the risk of kidney problems in certain people, especially with improper use or existing kidney disease.”
If you have a specific medication in mind, I can explain its actual kidney risks and who should be cautious.

